| Data | Casa | Visitante | Resultado |
|---|---|---|---|
| 16-09-25 17:45 | Athletic Bilbao | FC Arsenal | -:- |
| 16-09-25 17:45 | PSV Eindhoven | Royale Union Saint-Gilloise | -:- |
| 16-09-25 20:00 | Tottenham Hotspurs | FC Villarreal | -:- |
| 16-09-25 20:00 | Benfica | Qarabag | -:- |
| 16-09-25 20:00 | Juventus Turim | Borussia Dortmund | -:- |
| 16-09-25 20:00 | Real Madrid | Olympique Marselha | -:- |
| 17-09-25 17:45 | Olympiakos Pireu | Pafos FC | -:- |
| 17-09-25 17:45 | Slavia Praga | FK Bodö/Glimt | -:- |
| 17-09-25 20:00 | Paris St. Germain | Atalanta Bergamo | -:- |
| 17-09-25 20:00 | FC Liverpool | Atlético Madrid | -:- |
| 17-09-25 20:00 | Ajax Amsterdão | Inter Milão | -:- |
| 17-09-25 20:00 | FC Bayern Munique | FC Chelsea | -:- |
| 18-09-25 17:45 | FC Brugges | AS Mónaco | -:- |
| 18-09-25 17:45 | FC Copenhaga | Bayer 04 Leverkusen | -:- |
| 18-09-25 20:00 | Sporting | Qairat Almaty | -:- |
| 18-09-25 20:00 | Eintracht Frankfurt | Galatasaray Istambul | -:- |
| 18-09-25 20:00 | Manchester City | SSC Nápoles | -:- |
| 18-09-25 20:00 | Newcastle United | FC Barcelona | -:- |